Rapid reduction in parvalbumin concentration during chronic stimulation of rabbit fast twitch muscle

FEBS Letters

Klug, Gary¹  Pette, Dirk¹  Reichmann, Heinz¹ 

[1] Fakultät für Biologie, Universität Konstanz, Postfach 5560, D-7750 Konstanz, FRG

关键词: Fast and slow twitch muscle;    Chronic stimulation;    Parvalbumin;    Ca2+;   

DOI  :  10.1016/0014-5793(83)80374-3

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Chronic indirect stimulation of fast twitch rabbit muscle induced a rapid reduction in parvalbumin concentration. When compared to the unstimulated contralateral muscle, parvalbumins were reduced to 55% following 6 days of stimulation. Prolonged stimulation further reduced parvalbumins so that they were undetectable after 28 days. The time course of these changes appears to be related with the previously observed changes in the sarcoplasmic reticulum.

【 授权许可】

Unknown