ANTISPASMODIC EFFECTS OF CITRUS AURANTIUM FLOWERS AQUEOUS EXTRACT ON UTERUS OF NON-PREGNANT RATS

Iranian journal of reproductive medicine

AMIRZARGAR ASHRAF¹  GHANAVATI MARYAM¹  OROOJAN ALI AKBAR¹  AHANGARPOUR AKRAM¹ 

关键词: CITRUS AURANTIUM;    PROPRANOLOL;    NALOXONE;    ANTISPASMODIC;    UTERUS;    RAT;   

DOI  :  

学科分类：药学、药理学、毒理学（综合）

来源: Shahid Sadoughi University of Medical Sciences, Yazd

【 摘 要 】

Background: Citrus aurantium is a small citrus tree, with scented white flowers. The C. aurantium is used in Asian herbal medicine primarily to treat digestive problems.Objective: The goal of this study is to investigate the effect of C. aurantium flower's aqueous extract on uterine contraction in presence of some known uterus stimulants.Materials and Methods: In experimental study 30 virgin Wistar rats 200-300gr were obtained. After laparatomy, a piece of Uterus was dissected out and mounted in an organ bath (10ml) containing De Jalon (29oC) and contracted by KCl (60mM), oxytocin (10mU/ml) and barium chloride (4mM) then the effect of C. aurantium flower's aqueous extract (1-8 mg/ml) on the uterine contractions was investigated. Uterus was separately incubated with propranolol (1

【 授权许可】

Unknown