IS KARYOTYPING AND Y CHROMOSOME MICRODELETION STUDY NECESSARY IN MEN CANDIDATE FOR ICSI?

Iranian journal of reproductive medicine

RADKHAH K.¹  SEDIGHI GILANI M.A.¹  NOUROUZI M.R.¹  GHAFARI S.R.¹  GOURABI H.¹  RANJBARAN A.R.¹ 

关键词: Y CHROMOSOME MICRODELETION;    KARYOTYPE;    INTRACYTOPLASMIC SPERM INJECTION (ICSI);   

DOI  :  

学科分类：药学、药理学、毒理学（综合）

来源: Shahid Sadoughi University of Medical Sciences, Yazd

【 摘 要 】

Background: The sperm count and function may be affected by karyotype abnormalities or microdeletion in Y chromosome. These genetic abnormalities can probably transmit to the children.Objective: In this study, we tried to determine the frequency of karyotype abnormalities and Y chromosome microdeletions in severe oligospermic or azoospermic men who fathered sons by ICSI.Materials and Methods: This study comprised of fathers who had at least a son with ICSI due to severe oligospermia or azoospermia. General examinations were done and blood sample were obtained for karyotype and Y chromosome studies.

【 授权许可】

Unknown