Quantification of regional myocardial wall motion by cardiovascular magnetic resonance

Quantitative Imaging in Medicine and Surgery

Kai Jiang¹  Xin Yu² 

[1] Departments of Biomedical Engineering, Case Center for Imaging Research,;Departments of Biomedical Engineering, Case Center for Imaging Research,Radiology, and Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio, USA

关键词: Cardiovascular disease (CVD);    cardiovascular magnetic resonance (CMR);    MR tissue tagging;    displacement-encoding with stimulated echoes (DENSE);   

DOI  :  10.3978/j.issn.2223-4292.2014.09.01

学科分类：外科医学

来源: AME Publications

【 摘 要 】

Cardiovascular magnetic resonance (CMR) is a versatile tool that also allows comprehensive and accurate measurement of both global and regional myocardial contraction. Quantification of regional wall motion parameters, such as strain, strain rate, twist and torsion, has been shown to be more sensitive to early-stage functional alterations. Since the invention of CMR tagging by magnetization saturation in 1988, several CMR techniques have been developed to enable the measurement of regional myocardial wall motion, including myocardial tissue tagging, phase contrast mapping, displacement encoding with stimulated echoes (DENSE), and strain encoded (SENC) imaging. These techniques have been developed with their own advantages and limitations. In this review, two widely used and closely related CMR techniques, i.e., tissue tagging and DENSE, will be discussed from the perspective of pulse sequence development and image-processing techniques. The clinical and preclinical applications of tissue tagging and DENSE in assessing wall motion mechanics in both normal and diseased hearts, including coronary artery diseases, hypertrophic cardiomyopathy, aortic stenosis, and Duchenne muscular dystrophies, will be discussed.

【 授权许可】

Unknown