A Coumarin-based Fluorescent Sensor for Selective Detection of Copper (II)

Bulletin of the Korean chemical society

Zhao-Yang Luo¹  Jian-Hong Wang¹  Jin Zhao¹  Xin-Ling Guo¹  Xu-Feng Hou¹  Hui-Jun Zhao¹ 

关键词: Coumarin;    Cu2+ detection;    Confocal fluorescent;    Biological imaging;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Cu (II) detection is of great importance owing to its significant function in various biological processes. In this report, we developed a novel coumarin-based chemosensor bearing the salicylaldimine unit (2) for Cu2+ selective detection. The results from fluorescence spectra demonstrated that the sensor could selectively recognize Cu2+ over other metal cations and the detection limit is as low as 0.2 μM. Moreover, the confocal fluorescence imaging in HepG2 cells illustrated its potential for biological applications.

【 授权许可】

Unknown