Novel Synthesis of 3-Phenyl-chromen-4-ones Using N-Heterocyclic Carbene as Organocatalyst: An Efficient Domino Catalysis Type Approach

Bulletin of the Korean chemical society

Divya Singh¹  Shahin Fatma¹  Sarita Singh¹  Jagdamba Singh¹  Priya Mishra¹  Preyas Ankit¹ 

关键词: Umpolung;    Heterocycles;    Thiamine (N-Heterocyclic carbene);    Domino catalysis;    Natural Products;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Herein is reported a simple and efficient synthesis of isoflavones starting from various substituted phenacyl bromides and salicylaldehydes in presence of NHC. The mechanism involved domino catalysis type approach with consumption and regeneration of catalyst in two catalytic cycles. This method proved to be very lucrative and gives very good yield. The method described here represents an environmentally benign alternative to classical approach.

【 授权许可】

Unknown