Development of Multi-sample Loading Device for TEM Characterization of Hydroxyapatite Nanopowder

Bulletin of the Korean chemical society

Youn-Joong Kim¹  Jung-Kyun Kim¹  Eunji Lee¹  Jin-Gyu Kim¹  Jong-Man Jeong¹  Jong-Moon Lee¹ 

关键词: Internal standard;    Structure analysis;    Multi-sample loading device;    Transmission electron microscopy (TEM);    Hydroxyapatite nanopowder;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

A shortcoming of using transmission electron microscopy (TEM) for structural analysis via electron diffraction is the relatively large error of the measurements as compared to X-ray diffraction. To reduce these errors, various internal standard methods from earlier studies have been widely used. We developed a new device to facilitate the application of internal standard methods in preparation of TEM grids used for nanopowder analysis. Through the application of a partial mask on the TEM grid, both the internal standards and the research materials can be loaded on the same grid. Through this process, we conducted a TEM analysis that compared synthetic hydroxyapatite (HAp) nanopowder to bone apatite from a bovine femur. We determined that the accuracy of the d-spacing measurements of the HAp and bone powders could be improved to better than 1% after statistical treatments of the experimental data. By applying a quarter mask, we loaded four different nanoparticles on a single TEM grid, with one section designated for the internal standard.

【 授权许可】

Unknown