Open Tubular Molecular Imprinted Polymer Fabricated in Silica Capillary for the Chiral Recognition of Neutral Enantiomers in Capillary Electrochromatography

Bulletin of the Korean chemical society

Zeid A. ALOthman¹  Shabi Abbas Zaidi¹  Song Hee Yang¹  Won Jo Cheong¹  Abdullah M. ALMajid¹ 

关键词: Neutral template;    Molecule imprinted polymer;    Chiral separation;    Open tubular capillary;    Capillary electrochromatography;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

In this study, we have expanded the applicability of the pre-established generalized preparation protocol to MIPs with a neutral template. The (4S,5R)-4-methyl-5-phenyl-2-oxazolidinone MIP layer was formed inside a pretreated and silanized fused silica capillary, and its chiral separation performance was examined. Optimization of chiral separation was also carried out. This is the very first report of somewhat successful application of the generalized preparation protocol to a MIP with a genuine neutral template.

【 授权许可】

Unknown