One-pot, Three-component Synthesis of Fully Substituted 1,3,4-Oxadiazole Derivatives from (N-isocyanoimino)triphenylphosphorane, Aromatic Carboxylic acids and (1R)-(−)-Campherchinon

Bulletin of the Korean chemical society

Ali Ramazani¹  Behnaz Abdian¹  Fatemeh Zeinali Nasrabadi¹  Morteza Rouhani¹ 

关键词: (N-Isocyanimino)triphenylphosphorane;    (1R)-(−)-Campherchinon;    Aromatic carboxylic acid;    1;    3;    4-Oxadiazole;    aza-Wittig reaction;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Reactions of (N-isocyanimino)triphenylphosphorane with (1R)-(−)-campherchinon in the presence of aromatic carboxylic acids proceed smoothly at room temperature and in neutral conditions to afford sterically congested 1,3,4-oxadiazole derivatives in high yields. The reaction proceeds smoothly and cleanly under mild conditions and no side reactions were observed.

【 授权许可】

Unknown