Four-Component Preparation of Disubstituted 1,3,4-Oxadiazoles from (N-isocyanimino)triphenylphosphorane, Phenylacetylenecarboxylic Acid, Biacetyl and Primary Amines

Bulletin of the Korean chemical society

Nahid Shajari¹  Zahra Ranjdoost¹  Ali Ramazani¹  Behnaz Abdian¹  Fatemeh Zeinali Nasrabadi¹ 

关键词: (N-Isocyanimino)triphenylphosphorane;    Biacetyl;    Phenylacetylenecarboxylic acid;    Primary amine;    1;    3;    4-Oxadiazole;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

A simple method has been developed for four-component synthesis of disubstituted 1,3,4-oxadiazoles using (N-isocyanimino)triphenylphosphorane, a primary amine, a carboxylic acid and biacetyl in CH2Cl2 by the Ugi- 4CR/aza-Wittig sequence at room temperature in excellent yields.

【 授权许可】

Unknown