期刊论文详细信息
Bulletin of the Korean chemical society | |
Four-Component Synthesis of 2-(N,N-Dialkylamino)-2,4,6-Cycloheptatrien-1-One Derivatives from Tropolone, an Isocyanide, a Primary Amine and an Aldehyde via Ugi-Smiles Coupling Reaction | |
Issa Amini1  Yavar Ahmadi1  Ali Ramazani1  Fatemeh Zeinali Nasrabadi1  Abdolhossain Massoudi1  | |
关键词: Tropolone; Isocyanides; Primary amines; Aldehydes; Ugi-Smiles-type reaction; | |
DOI : | |
学科分类:化学(综合) | |
来源: Korean Chemical Society | |
【 摘 要 】
The use of Smiles rearrangement in Ugi-type couplings with tropolone allows very straightforward multicomponent formation of 2-(N,N-dialkylamino)-2,4,6-cycloheptatrien-1-one derivatives. The Ugi four-component reaction of isocyanides with tropolone (2-hydroxy-2,4,6-cycloheptatrien-1-one), primary amines and aldehydes proceeds smoothly and cleanly under mild conditions to afford 2-(N,N-dialkylamino)-2,4,6-cycloheptatrien- 1-one derivatives in fairly good yields.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912010243315ZK.pdf | 185KB | download |