Synthesis, Characterization and Study Biological Activity of New Para-methoxy Benzene Sulfonamide Derivatives and some Amino Acid

2nd International Scientific Conference (Pure Sciences, Brilliant Creativity and Renewed Building)

Awad, Sana Hitur^1^2 ; Sahib, Sana Abdul^1^2 ; Hussein, Fatimah Ali^1^2 ; Hasan Al-Khfaji, Hussein Abdulkadhim^1^2

University of Baghdad, College of Science for Women Iraq, Baghdad, Iraq^1

University of Babylon, College of Science, Department of Chemistry, Babylon, Iraq^2

关键词: Alkaline medium;    Amine groups;    Anti-bacterial;    Antibacterial properties;    Methoxybenzene;    Primary amines;    Sulfonamide derivatives;    Sulphonamides;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/571/1/012093/pdf
DOI  :  10.1088/1757-899X/571/1/012093

来源: IOP

【 摘 要 】

The synthesis of para-methoxy sulphonamides [3a-3G] was obtained by reacting p-methoxy benzene sulphonyl chloride with primary amine functionalities of amine group [1a-1G] in alkaline medium at temperature below 0°C, structures of all Newly synthesized compound were analysed by FT-IR, H and CNMR spectroscopy, Anti bacterial of the titled compounds were screened and the compounds exhibited potent anti bacterial properties.