Carbon-based Solid Acid Catalyzed One-pot Mannich Reaction: A Facile Synthesis of β-Amino Carbonyl Compounds

Bulletin of the Korean chemical society

Niloofar Tavakoli Hoseini¹  Abolghasem Davoodnia¹  Afsaneh Tavakoli Nishaburi¹ 

关键词: Carbon-based solid acid;    Mannich reaction;    -Amino carbonyl compounds;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

A simple and efficient method for the synthesis of β-amino carbonyl compounds by one-pot three-component Mannich reaction of acetophenone, aromatic aldehydes and aromatic amines using a carbon-based solid acid (CBSA), as an effective and reusable catalyst, is described. The present methodology offers several advantages such as simple procedure with an easy work-up, shorter reaction times, and high yields.

【 授权许可】

Unknown