Convergent Synthesis and Characterization of Dumbbell Type Dendritic Materials by Click Chemistry

Bulletin of the Korean chemical society

Sung-Ho Jin¹  Jae Wook Lee¹  Sae Reum Sung¹  Seung Choul Han¹ 

关键词: Alkyne;    Azide;    Click reaction;    Dendritic-linear-dendritic materials;    Dendrimer;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

General, fast, and efficient stitching methods for the synthesis of dendrimers with linear PEG units at a core, as dendritic-linear-dendritic materials, were developed. The synthetic strategy involved the click reaction between an alkyne and an azide. The linear core building blocks, three dialkyne-PEG units, were chosen to serve as the alkyne functionalities for dendrimer growth via click reactions with the azide-dendrons. These three building blocks were employed together with the azide-functionalized Fréchet-type dendrons in a convergent strategy to synthesize the Fréchet-type dendrimers with different linear core units. Their structure of dendrimers was confirmed by 1H and 13C NMR spectroscopy, IR spectroscopy, mass spectrometry, and GPC analysis.

【 授权许可】

Unknown