Microwave Assisted One-pot Synthesis of Novel ¥á-Aminophosphonates and Their Biological Activity

Bulletin of the Korean chemical society

Alahari Janardhan Rao¹  Pasupuleti Visweswara Rao¹  Challamchalla Mohan¹  Cirandur Suresh Reddy¹  Valsani Koteswara Rao¹  Chamarthi Naga Raju¹ 

关键词: Aminophosphonates;    Microwave irradiation;    Gram positive bacteria;    Gram negative bacteria;    Anti-oxidant activity;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

A simple and efficient synthesis of various �?-aminophosphonates (3a-l) by the reaction of substituted aromatic/heterocyclic aldehydes, 2-amino-6-methoxy-benzothiazole and dibutyl/diphenyl phosphites under microwave irradiation without catalyst was accomplished. The phosphonates were characterized by elemental analysis, IR, ¹H, ¹³C- and ³¹PNMR spectra. They showed promising antimicrobial, anti-oxidant activities depending on the nature of bioactive groups at the �?-carbon.

【 授权许可】

Unknown