Actividad inhibitoria del crecimiento bacteriano por cobre nanoestructurado obtenido de minerales de la región Marañón: comparación con cobre comercial

Revista Peruana de Biologia

Ramirez, Pablo¹  Lovera, Daniel¹  Eca, Anika¹  Landauro, Carlos V¹  Bernaldo, Jordán¹  Pillaca, Mirtha¹  Sánchez-Venegas, Jaime¹ 

[1] Universidad Nacional Mayor de San Marcos, Lima, PERÚ

关键词: Growth inhibitory activity;    Gram positive bacteria;    Gram negative bacteria;    copper nanoparticles;    mechanical milling.;   

DOI  :  10.15381/rpb.v23i3.12866

学科分类：生物科学（综合）

来源: Universidad Nacional Mayor de San Marcos * Facultad de Ciencias Biologicas

【 摘 要 】

In this paper, we report on the bacterial growth inhibitory activity of nanoparticles of cemented and commercial copper. Strains of Staphylococcus aureus ATCC 6538 (Gram positive) and Escherichia coli ATCC 35218 (Gram negative) were used to determine the inhibitory effect by the minimal inhibitory concentration of the nanoparticles diluted in nutrient culture broth and distributed in ELISA plates. The copper cements (obtained from hydrometallurgical processes) and the commercial one were nanostructured employing a mechanical milling equipment. The results indicate that commercial copper nanoparticles (after 2.5 hours of milling) show growth inhibitory action of S. aureus strain. However, in the case of E. coli strains no inhibitory action has been observed. It was also determined that the minimal inhibitory concentration of the commercial copper is 20 μg/mL against S. aureus. On the other hand, copper cements (in solid and nanostructured form) do not show inhibitory effects.

【 授权许可】

CC BY-NC