Performance Characteristic of the ¥â-Human Chorionic Gonadotropin Assay on the Access 2 for Its Use in Doping Control

Bulletin of the Korean chemical society

Sang Mi Shin¹  Changbae Jin¹  Oh Seung Kwon¹  Bong Chul Chung¹  Hyeim Lee¹  Min Jung Kang¹  Hye Hyun Yoo¹ 

关键词: ¥â-hCG;    Access 2;    Doping control;    Method evaluation;    Confirmation method;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

The objective of this study was to validate performance characteristics of the Access 2 (Beckman coulter) system for hCG assays for use as a confirmation test for doping control. The Access 2 assay was linear up to 500 IU/L. The correlation coefficient was higher than 0.999, and the sensitivity of the linearity was 0.82. There were no false positive or false negative cases. LOD was 0.59 IU/L. The method was robust when performed by different people. Repeatability and reproducibility were below 7%. We compared reproducibility and recoveries of Access 2 and Elecsys 2010. Access 2 demonstrated higher reproducibility than Elecsys 2010. Recoveries (accuracy) of Access 2 were between 85 and 105%. Recoveries for Elecsys 2010 were between 91 and 104%.

【 授权许可】

Unknown