Nanocrystalline Copper Oxide(II)-Catalyzed Alkyne-Azide Cycloadditions

Bulletin of the Korean chemical society

Young-Jin Song¹  Chungyul Yoo¹  Jong-Tai Hong¹  Seung Uk Son¹  Hye-Young Jang¹  Seung-Joo Kim¹ 

关键词: Click chemistry;    Copper oxide nanoparticles;    Cycloaddition;    Heterogeneous catalysis;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Although the use of Cu(II) salts as catalysts without reductants is limited in the cycloaddition of acetylenes with azides, the catalytic system employing average 10 nm CuO(II) nanoparticles in the absence of reductants shows good catalytic activity to form 1,4-disubstituted 1,2,3-triazoles even in wet THF as well as water. It is also noticeable that CuO(II) nanoparticle catalysts can be recycled with consistent activity. A range of alkynes and azides were subject to the optimized CuO(II) nanoparticle-catalyzed cycloaddition reaction conditions to afford the desired products in good yields.

【 授权许可】

Unknown