Synthesis of Novel Mercaptophenyl Carbocyclic C-Nucleoside Analogue Using Sequential [3,3]-Sigmatropic Rearrangement and Ring-closing Metathesis

Bulletin of the Korean chemical society

Joon Hee Hong¹  Hua Li¹ 

关键词: Carbocyclic C-nucleoside;    [3;    3]-Sigmatropic rearrangement;    Ring-closing metathesis;    Friedel-Crafts alkylation;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Novel mercaptophenyl carbocyclic C-nucleoside analogue was synthesized via a cyclopentenol intermediate 10, which was prepared using a sequential [3,3]-sigmatropic rearrangement and ring-closing metathesis (RCM). Friedel-Crafts alkylation was then used to couple the thiophenol.

【 授权许可】

Unknown