Intercalation of Vitamer into LDH and Their Controlled Release Properties

Bulletin of the Korean chemical society

You-Hwan Son¹  Jin-Ho Choy¹ 

关键词: Layered double hydroxide (LDH);    Vitamins;    Intercalation;    Controlled release;    Safe delivery;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Biofunctional nanohybrids are synthesized from layered double hydroxide (LDH) and the vitamins such as ascorbic acid and topopherol acid succinate. Either ion exchange or copricipitaion leads to successful intercalation of the vitamins into gallery space of LDH that offers a new route to safe preservation of bioactivity as well as controlled release. Intercalations of vitamins are clearly reflected on the increase in the basal spacing of ZnAl-(Nitrate) LDH from 8.5 �? to 10.5 �? for ascorbate, and 49.0 �? for tocopherol acid succinate, respectively. No significant change in UV-Vis and IR absorption characteristics of the intercalated vitamins strongly supports the safe maintenance of their bioactivities without any deterioration of chemical and structural integrity. Furthermore, it is shown that the hybridized vitamins could be discharged in a controlled kinetics.

【 授权许可】

Unknown