Chitosan-carboxymethylcellulose based microcapsules formulation for controlled release of active ingredients from cosmeto textile

17th World Textile Conference AUTEX 2017 - Shaping the Future of Textiles

Roy, J.C.^1,2,3,4 ; Ferri, A.^1 ; Salaün, F.^2,3 ; Giraud, S.^2,3 ; Chen, G.^4 ; Jinping, G.^4

Department of Applied Science and Technology, Politecnico di Torino, Torino, Italy^1

University Lille Nord de France, Lille

F-5900, France^2

ENSAIT, GMTEX, Roubaix

F-59100, France^3

College of Textile and Clothing Engineering, Soochow University, Jiangsu, China^4

关键词: Active ingredients;    Carboxymethyl cellulose;    Controlled release;    Degradation temperatures;    Dynamic scanning;    Emulsion droplets;    Encapsulation efficiency;    Microencapsulation process;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/254/7/072020/pdf
DOI  :  10.1088/1757-899X/254/7/072020

来源: IOP

【 摘 要 】

Chitosan-based emulsions were prepared at pH from 4.0 to 6.0. The zeta potential and droplet size were monitored at different pH. Double emulsions (wateroil- water) were observed due to the stiff conformation of chitosan at pH 4.0. At pH 5.0, the emulsion droplets were the smallest (2.9 μm) of the experimental pH range. The emulsion droplets were well dispersed due to high surface charge of chitosan (for example, +50 mV at pH 5.5) in entire pH range. The emulsion was treated with carboxymethyl cellulose (CMC) for neutralizing the charged chitosan on the surface of emulsion droplets. Above 10×10-2mg/ml of CMC, no change in zeta potential was observed indicating no more free chitosan existed after neutralization with CMC. The emulsion was then crosslinked with different amount of glutaraldehyde. Upon increasing the amount of glutaraldehyde, the amount of core content inside the microcapsule and encapsulation efficiency of shell materials decreased gradually. The Dynamic Scanning Calorimetry data confirmed no interaction between core and shell material in the microencapsulation process. The thermal degradation of the microcapsules was examined by thermogravimetric analysis and a gradual decrease in the degradation temperature upon increasing glutaraldehyde concentration was found. The tuning of CMC concentration can provide valuable information regarding stable emulsion and efficient microcapsule formulation via coacervation.