The Matrix Effect of Biological Concomitant Element on the Signal Intensity of Ge, As, and Se in Inductively Coupled Plasma/Mass Spectrometry

Bulletin of the Korean chemical society

Sun-Tae Kim¹  Won Lee¹  Kyung-Su Park¹  Young-Man Kim¹  Yunje Kim¹ 

关键词: Matrix effect;    Serum;    Urine;    ICP/MS;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

The non-spectroscopic interference effects that occurred in inductively coupled plasma/mass spectrometry were studied for Ge, As and Se in human urine and serum. Many biological samples contain Na, K, Cl and organic compounds, which may cause the enhancement and depression on the analyte signal. The effect of 1% concomitant elements such as N, Cl, S, P, C, Na, and K on a 100 Ф/L germanium, arsenic and selenium signal has been investigated by ICP/MS. The interference effects were not in the same direction. It appeared that concomitant elements such as Cl, S, and C induce an enhancement effect, whereas N and P did not show any significant effect. And, Na and K caused a depression. We have found a link between the abundance of analytes and the ionization potential of concomitant elements (eV), except carbon and nitrogen.

【 授权许可】

Unknown