Proposed Addendum to Previously Published Fetal Dose Estimate Tables for 18F-FDG

Journal of Nuclear Medicine

Michael G. Stabin¹ 

[1] Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, Tennessee Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, Tennessee Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, Tennessee

关键词: PET;    radiobiology/dosimetry;    radiopharmaceuticals;    dosimetry;    ¹⁸F-FDG;    pregnancy;   

DOI  :  

学科分类：医学（综合）

来源: Society of Nuclear Medicine

【 摘 要 】

Placental transfer and fetal dose estimates have been published for women in early pregnancy and at the end of each trimester for a large number of radiopharmaceuticals. For the case of 18F-FDG, a dose was given with no information about placental transfer of the radiopharmaceutical. Recent publications have reported quantitative values for maternal and fetal uptake of 18F-FDG in primates and new values for 18F-FDG kinetics. In this article, these data are applied to give radiation dose estimates for the fetus at all stages of pregnancy for 18F-FDG. The recommended values are 2.2 × 10−2 mGy/MBq in early pregnancy, 2.2 × 10−2 mGy/MBq at 3-mo gestation, 1.7 × 10−2 mGy/MBq at 6-mo gestation, and 1.7 × 10−2 mGy/MBq at 9-mo gestation.

【 授权许可】

Unknown