Synthesis and Characterization of Novel Oxadiazole Derivatives from Benzimidazole

Journal of the Korean Chemical Society

Bannimath Gurupadayya¹  Balasubramanaya Vishwanathan¹ 

关键词: Benzimidazole;    Oxadiazole;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

In the present study, a series of novel N-(1H-benzo[d]imidazol-2-yl)methyl-5-[(hetero)aryl-1,3,4-oxadiazol-2- yl]methanamine (4a-4j) were efficiently synthesized. Condensation of hydrazide derivative 3 with various carboxylic acid derivatives yielded N-[(1H-benzo[d]imidazol-2-yl)methy](5-substituted-1,3,4-oxadiazol-2-yl)methanamine (4a-4j) and compound 5-{[(1H-benzo[d]imidazol-2-yl)methylamino]methyl}-1,3,4-oxadiazole-2-thiol (4k) was obtained on treating hydrazide 3 with carbon disulfide. All the newly synthesized analogues were characterized by IR, 1H NMR, 13C NMR and mass spectral data.

【 授权许可】

Unknown