Considerations Regarding the Use of Blood Samples in the Proteomic Identification of Biomarkers for Cancer Diagnosis

Cancer Genomics - Proteomics

CHRISTINE V. SAPAN¹  ROGER L. LUNDBLAD¹ 

[1] Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7525, U.S.A. Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7525, U.S.A. Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7525, U.S.A.

关键词: Proteomics;    biomarkers;    blood plasma;    serum;    review;   

DOI  :  

来源: Delinasios GJ CO

【 摘 要 】

Blood is the most common source of biomarkers for use in the diagnosis and prognosis of malignant disease. Utilizing proteomic technology for biomarker identification offers greatly increased sensitivity. Such an increase in sensitivity requires precise sample preparation to eliminate any bias in analysis. Here, issues concerning the use of blood, plasma and serum for proteomic analysis are summarized.

【 授权许可】

Unknown