Technical Requirements for Na18F PET Bone Imaging of Patients Being Treated Using a Taylor Spatial Frame

Journal of Nuclear Medicine Technology

Hans Jacobsson¹  Fredrik Brolin¹  Anders Sundin¹  Åsa Oldner¹  Cathrine Jonsson¹  Henrik Lundblad¹  Marilyn E. Noz¹  Gerald Q. Maguire¹  Robert Hatherly¹ 

关键词: Na¹⁸F;    PET/CT;    bone imaging;    Taylor spatial frame;   

DOI  :  10.2967/jnmt.113.133082

学科分类：医学（综合）

来源: Society of Nuclear Medicine

【 摘 要 】

Diagnosis of new bone growth in patients with compound tibia fractures or deformities treated using a Taylor spatial frame is difficult with conventional radiography because the frame obstructs the images and creates artifacts. The use of Na18F PET studies may help to eliminate this difficulty. Methods: Patients were positioned on the pallet of a clinical PET/CT scanner and made as comfortable as possible with their legs immobilized. One bed position covering the site of the fracture, including the Taylor spatial frame, was chosen for the study. A topogram was performed, as well as diagnostic and attenuation correction CT. The patients were given 2 MBq of Na18F per kilogram of body weight. A 45-min list-mode acquisition was performed starting at the time of injection, followed by a 5-min static acquisition 60 min after injection. The patients were examined 6 wk after the Taylor spatial frame had been applied and again at 3 mo to assess new bone growth. Results: A list-mode reconstruction sequence of 1 × 1,800 and 1 × 2,700 s, as well as the 5-min static scan, allowed visualization of regional bone turnover. Conclusion: With Na18F PET/CT, it was possible to confirm regional bone turnover as a means of visualizing bone remodeling without the interference of artifacts from the Taylor spatial frame. Furthermore, dynamic list-mode acquisition allowed different sequences to be performed, enabling, for example, visualization of tracer transport from blood to the fracture site.

【 授权许可】

Unknown