The Role of Thallium Scintimammography with Lateral Decubitus Positioning in the Diagnosis of Breast Cancer

Journal of Nuclear Medicine Technology

E.R. Conklin¹  J. Hunt-Mozgala¹  G.J. Wasserstein¹  J.S. Deitch¹  E.T. Cancroft¹  C. Cabahug¹  J.W. Weitz¹  Z.H. Oster¹  P.A. Bardfeld¹ 

[1] Division of Nuclear Medicine, Department of Radiology, Nassau County Medical Center, East Meadow, New York; and Division of Nuclear Medicine, Department of Radiology, State University of New York Health Science Center at Stony Brook, Stony Brook, New York Division of Nuclear Medicine, Department of Radiology, Nassau County Medical Center, East Meadow, New York; and Division of Nuclear Medicine, Department of Radiology, State University of New York Health Science Center at Stony Brook, Stony Brook, New York Division of Nuclear Medicine, Department of Radiology, Nassau County Medical Center, East Meadow, New York; and Division of Nuclear Medicine, Department of Radiology, State University of New York Health Science Center at Stony Brook, Stony Brook, New York

关键词: scintimammography;    thallium-201;    breast cancer;   

DOI  :  

学科分类：医学（综合）

来源: Society of Nuclear Medicine

【 摘 要 】

Objective: Many different positioning techniques have been attempted in the search for the best method of imaging the breast during scintimammography. A new, effective and comfortable method of positioning the breast is described. Thallium-201-chloride is further explored as an agent to detect breast cancer.Methods: Forty-two women with either a palpable mass or abnormal mammogram were imaged in the lateral decubitus and anterior supine positions. Each patient was injected intravenously with 75–112.5 MBq (2–3 mCi) of 201TI-chloride. Planar images of 10–15 min each were obtained beginning 10 min after injection.Results: Lateral decubitus positioning was very comfortable for the patient and afforded maximum privacy. High-quality images were obtained with breast tissue and axilla clearly visualized. Breast-to-camera distance was minimized to less than 0.5 inch in many cases. The sensitivity of thallium scintimammography was 90% and the specificity was 86% in 26 lesions with pathologic correlation. The smallest lesion detected measured 0.8 cm.Conclusion: Lateral decubitus positioning in scintimammography provides an alternative to prone positioning which is sensitive, comfortable and private. Thallium-201 scintimammography employing lateral decubitus positioning has an acceptable sensitivity and specificity for detecting breast carcinoma.

【 授权许可】

Unknown