期刊论文详细信息
PLOS Pathogens
Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine
Jeronimo Cello1  Diana Edo-Matas1  Jerome H. H. V. Custers1  Eckard Wimmer1  Roland Zahn1  Gillian Cooper1  Tobias Kamphuis1  Isabel de los Rios Oakes1  Vladimir van Hoek1  Yutong Song1  Javier Martín1  Taco G. Uil1  John Lewis1  Barbara P. Sanders1  Hanneke Schuitemaker1  Laura E. Crawt1  Viki Bockstal1 
关键词: Viral replication;    Poliovirus;    Vaccines;    Microbial mutation;    Antigens;    RNA viruses;    Internal ribosome entry site;    Attenuated vaccines;   
DOI  :  10.1371/journal.ppat.1005483
学科分类:生物科学(综合)
来源: Public Library of Science
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