An Epigenetic Compound Library Screen Identifies BET Inhibitors That Promote HSV-1 and -2 Replication by Bridging P-TEFb to Viral Gene Promoters through BRD4

PLOS Pathogens

Yayi Hou¹  Wei Zhang¹  Erguang Li¹  Xiaoqing Chen¹  Yue Dai¹  Yimei Fan¹  Ren Xiang Tan¹  Yingyu Ma¹  Ke Ren¹ 

关键词: DNA transcription;    Gene regulation;    Herpes simplex virus;    Library screening;    Viral genes;    Epigenetics;    Herpes simplex virus-1;    Viral replication;   

DOI  :  10.1371/journal.ppat.1005950

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

Unknown