An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression

PLOS Pathogens

Olivier Rohr¹  Benoit Van Driessche¹  Gilles Darcis¹  Jean-Stéphane Gatot¹  Lucio Gama¹  Amina Ait-Ammar¹  Stéphane De Wit¹  B. Matija Peterlin¹  Nathan Clumeck¹  Adeline Melard¹  Arsène Burny¹  Thomas Cherrier¹  Christian Schwartz¹  Nadège Delacourt¹  Carine Van Lint¹  Anna Kula¹  Francis Corazza¹  Michel Moutschen¹  Jorge Vila¹  Kabamba Kabeya¹  Sophie Bouchat¹  Caroline Vanhulle¹  Koh Fujinaga¹  Luiz F. Pianowski¹  Christine Rouzioux¹ 

关键词: HIV-1;    T cells;    Viral replication;    Drug therapy;    Cell cultures;    HIV;    Flow cytometry;    Viral persistence and latency;   

DOI  :  10.1371/journal.ppat.1005063

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

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