Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing

PLOS Pathogens

Jonathan Spindler¹  Kirsten M. Stray¹  Mini Balakrishnan¹  Joseph Hesselgesser¹  John Mellors¹  Michael Graupe¹  Celsa A. Spina¹  Datsen George Wei¹  Jeffrey P. Murry¹  Mary Kearney¹  Alivelu Irrinki¹  Helen Yu¹  Tomas Cihlar¹  Angela Tsai¹  Vicki Chiang¹  Deborah McMahon¹  Derek Sloan¹  Tiffany Barnes¹  Romas Geleziunas¹  George Stepan¹  Elizabeth Fyne¹  Jacob Lalezari¹ 

关键词: HIV;    T helper cells;    Memory T cells;    T cells;    RNA extraction;    Flow cytometry;    HIV infections;    Memory;   

DOI  :  10.1371/journal.ppat.1004071

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

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