Random Codon Re-encoding Induces Stable Reduction of Replicative Fitness of Chikungunya Virus in Primate and Mosquito Cells

PLOS Pathogens

Edward C. Holmes¹  Ernest A. Gould¹  Fabien Aubry¹  Xavier de Lamballerie¹  Antoine Nougairede¹  Lauriane De Fabritus¹ 

关键词: Viral replication;    Microbial mutation;    Chikungunya virus;    Vero cells;    Chikungunya infection;    Deletion mutation;    Mutation detection;    Primates;   

DOI  :  10.1371/journal.ppat.1003172

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

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