A Major Determinant of Cyclophilin Dependence and Cyclosporine Susceptibility of Hepatitis C Virus Identified by a Genetic Approach

PLOS Pathogens

Ralf Bartenschlager¹  Vanesa Madan¹  Andrew E. Greenstein¹  Feng Yang¹  Jason M. Robotham¹  Margarita Zayas¹  Henry Grise¹  Ewa Bienkiewicz¹  Anita Nag¹  Stephen Frausto¹  Hengli Tang¹  Margaret Robinson¹  Timothy M. Logan¹ 

关键词: Proline;    Microbial mutation;    Cofactors (biochemistry);    Viral replication;    Sequence motif analysis;    Hepatitis C virus;    Antimicrobial resistance;    Point mutation;   

DOI  :  10.1371/journal.ppat.1001118

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

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