Use of Tissue-Specific MicroRNA to Control Pathology of Wild-Type Adenovirus without Attenuation of Its Ability to Kill Cancer Cells

PLOS Pathogens

Fionnadh Carroll¹  Hannah H. Chen¹  Miriam Bazan-Peregrino¹  Ryan Cawood¹  Leonard W. Seymour¹  Nico van Rooijen¹ 

关键词: MicroRNAs;    Viral replication;    Adenoviruses;    Luciferase;    Cell binding;    Plasmid construction;    Mammalian genomics;    Toxicity;   

DOI  :  10.1371/journal.ppat.1000440

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

Unknown