Multiple causes of death related to Chagas' disease in Brazil, 1999 to 2007

Revista da Sociedade Brasileira de Medicina Tropical

James Cook University, Townsville, Australia¹  Heukelbach, Jorg¹  University of Basel, Basel, Switzerland¹  Martins-Melo, Francisco Rogerlândio¹  Ramos Junior, Alberto Novaes¹  Universidade Federal do Ceará, Fortaleza¹  Alencar, Carlos Henrique¹ 

关键词: Chagas' disease;    Mortality;    Underlying cause of death;    Multiple causes of death;    Epidemiology;    Brazil;   

DOI  :  10.1590/S0037-86822012000500010

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

INTRODUCTION: Chagas' disease is a major public health problem in Brazil and needs extensive and reliable information to support consistent prevention and control actions. This study describes the most common causes of death associated with deaths related to Chagas' disease (underlying or associated cause of death).METHODS: Mortality data were obtained from the Mortality Information System of the Ministry of Health (approximately 9 million deaths). We analyzed all deaths that occurred in Brazil between 1999 and 2007, where Chagas' disease was mentioned on the death certificate as underlying or associated cause (multiple causes of death).RESULTS: There was a total of 53,930 deaths related to Chagas' disease, 44,543 (82.6%) as underlying cause and 9,387 (17.4%) as associated cause. The main diseases and conditions associated with death by Chagas' disease as underlying cause included direct complications of cardiac involvement, such as conduction disorders/arrhythmias (41.4%) and heart failure (37.7%). Cerebrovascular disease (13.2%), ischemic heart disease (13.2%) and hypertensive diseases (9.3%) were the main underlying causes of deaths in which Chagas' disease was identified as an associated cause.CONCLUSIONS: Cardiovascular diseases were often associated with deaths related to Chagas' disease. Information from multiple causes of death recorded on death certificates allows reconstruction of the natural history of Chagas' disease and suggests preventive and therapeutic potential measures more adequate and specifics.

【 授权许可】

Unknown