Risk factors for Leishmania chagasi infection in an endemic area in Raposa, State of Maranhão, Brazil

Revista da Sociedade Brasileira de Medicina Tropical

Cavalcante, Maria Neuza¹  Centro de Pesquisas Gonçalo Moniz, Salvador¹  Barral, Aldina Maria Prado¹  Ponte, Charlene Barreto¹  Caldas, Arlene de Jesus Mendes¹  Secretaria Municipal de Saúde São Luis¹  Aquino, Dorlene Maria Cardoso de¹  Souza, Natália Coelho¹  Universidade Federal do Maranhão, São Luis¹ 

关键词: Visceral leishmaniasis;    Kalazar;    Leishmania chagasi;    Montenegro skin test;    Risk factors;   

DOI  :  10.1590/S0037-86822011005000059

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

INTRODUCTION: Infection with Leishmania chagasi is the most common clinical presentation for visceral leishmaniaisis in endemic areas. The municipality of Raposa is an endemic area in State of Maranhão, Brazil, and have had registration cases of visceral leishmaniasis disease. For this reason, a cross- sectional study was conducted to evaluate the risk factors for infection with L. chagasi detected by Montenegro skin test.METHODS: The sample comprised 96% of the inhabitants of the villages of Maresia, Pantoja, and Marisol located in the municipality of Raposa, corresponding to 1,359 subjects. Data were collected using a questionnaire. Univariate and multivariate logistic regression models were applied to evaluate the association between the variables studied and infection of L. chagasi.RESULTS: The variables associated with infection upon nonadjusted analysis were a straw roof, mud walls, floors of beaten earth, presence of sand flies inside or outside of the dwelling, and bathing outdoors. Adjusted analysis showed that the presence of sand flies inside/outside the dwelling was a risk factor, and age younger than 10 years was a protective factor against asymptomatic infection.CONCLUSIONS: The results highlight the extent to which precarious living conditions of the population strengthen the epidemiological chain of visceral leishmaniasis.

【 授权许可】

Unknown