Viral etiology among the elderly presenting acute respiratory infection during the influenza season

Revista da Sociedade Brasileira de Medicina Tropical

Bellei, Nancy¹  Candeias, João Manuelo Grisi¹  Carraro, Emerson¹  Campinas State University, Campinas, Brazil¹  Donalísio, Maria Rita¹  Leal, Élcio¹  Federal University of Pará, Brazil¹  Watanabe, Aripuanã Sakurada Aranha¹  São Paulo State University, Botucatu, Brazil¹  São Paulo Federal University, Sao Paulo, Brazil¹  Granato, Celso Francisco Hernandes¹ 

关键词: Respiratory viruses;    Human rhinovirus;    Genescan RT-PCR;    Reverse transcription polymerase chain reaction;    Elderly;   

DOI  :  10.1590/S0037-86822011000100005

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

INTRODUCTION: Acute respiratory tract infections are the most common illness in all individuals. Rhinoviruses have been reported as the etiology of more than 50% of respiratory tract infections worldwide. The study prospectively evaluated 47 elderly individuals from a group of 384 randomly assigned for acute respiratory viral infections (cold or flu) and assessed the occurrence of human rhinovirus (HRV), influenza A and B, respiratory syncytial virus and metapneumovirus (hMPV) in Botucatu, State of São Paulo, Brazil.METHODS: Forty-nine nasal swabs collected from 47 elderly individuals following inclusion visits from 2002 to 2003 were tested by GenScan RT-PCR. HRV-positive samples were sequenced for phylogenetic analysis.RESULTS: No sample was positive for influenza A/B or RSV. HRV was detected in 28.6% (14/47) and hMPV in 2% (1/47). Of 14 positive samples, 9 isolates were successfully sequenced, showing the follow group distribution: 6 group A, 1 group B and 2 group C HRVs.CONCLUSIONS: The high incidence of HRV during the months of the influenza season requires further study regarding HRV infection impact on respiratory complications among this population. Infection caused by HRV is very frequent and may contribute to increasing the already high demand for healthcare during the influenza season.

【 授权许可】

Unknown