Primary cutaneous histoplasmosis: case report on an immunocompetent patient and review of the literature

Revista da Sociedade Brasileira de Medicina Tropical

Wanke, Bodo¹  Salgueiro, Mariza de Matos¹  Schubach, Armando de Oliveira¹  Lazera, Márcia¹  Conceição-Silva, Fátima¹  Saheki, Mauricio Naoto¹  Fundação Oswaldo Cruz, Rio de Janeiro¹ 

关键词: Primary cutaneous histoplasmosis;    Histoplasma capsulatum;    Itraconazole;   

DOI  :  10.1590/S0037-86822008000600024

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

This report describes a case of primary cutaneous histoplasmosis in a 45-year-old male. The presentation consisted of an erythematous nodule on the back of the right hand, accompanied by nontender regional lymphadenomegaly that developed following local trauma that occurred during military training in a tunnel inhabited by bats. Histological examination of a biopsy specimen from the skin lesion showed granulomatous infiltrate, but did not show fungal elements. Culturing of this material, incubated in Sabouraud agar, showed growth of Histoplasma capsulatum. No evidence of systemic involvement or immunosuppression was found. Treatment with 400 mg/day of itraconazole orally for six months resulted in complete remission of the lesion, which was maintained one year after the end of the treatment.

【 授权许可】

Unknown