Antimicrobial resistance of uropathogens among outpatients, 2000-2004

Revista da Sociedade Brasileira de Medicina Tropical

Fundação Universidade Federal do Rio Grande, Rio Grande¹  Müller, Fernanda Melo¹  Zhang, Linjie¹  Ribeiro, Juliana Camurça¹  Schnor, Otávio Haygert¹  Zimmermann, Bruno Sudbrack¹  D' Agostin, Juliana¹  Koch, Camila Ribeiro¹  Machado, Vívian¹ 

关键词: Urinary tract infection;    Bacterial resistance;    Antibiotics;    Urine culture;    Retrospective study;   

DOI  :  10.1590/S0037-86822008000300010

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

A retrospective study based on the electronic database of a university hospital was carried out to investigate the prevalence of etiological agents and their susceptibilities to antibiotics, among adult outpatients (> 18 years old) with urinary tract infections. Nine hundred and fifty-seven positive urine cultures were identified between January 2000 and December 2004. Escherichia coli, Proteus mirabilis and Klebsiella sp were the three principal bacterial etiological agents. Trimethoprim-sulfamethoxazole presented the highest prevalence of bacterial resistance (46.9%), followed by cefalotin (46.7%), nalidixic acid (27.6%) and nitrofurantoin (22.3%). Over the study period, nalidixic acid presented annual increases of 5.9% in the rate of bacterial resistance (p = 0.02). Ciprofloxacin also showed an increasing trend, of 3.3% per year (p = 0.07). This study demonstrated that the antibiotics that are widely recommended for empirical treatment of urinary tract infection in adults presented high rates of bacterial resistance among the population studied.

【 授权许可】

Unknown