Assessment of ivermectin therapeutic efficacy on fourth-stage larvae of Lagochilascaris minor in experimentally infected cats

Revista da Sociedade Brasileira de Medicina Tropical

Universidade Federal de Goiânia¹  Barbosa, Carlos Augusto Lopes¹  Campos, Dulcinéa Maria Barbosa¹ 

关键词: Ivermectina;    Lagochilascaris minor;    Fourth-stage larvae;   

DOI  :  10.1590/S0037-86822001000400011

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

In order to verify the action of ivermectin against fourth-stage larvae of Lagochilascaris minor, thirty cats were divided into three groups (I, II and III). Each animal was inoculated orally with 50 third-stage larvae. The cats from groups I and II were treated with Ivermectin (200/mg/kg/single dose/sc via) on fifth day after inoculation (DAI). Treatment evaluation was performed between 30 and 40 DAI (group I) and between 180 to 190 DAI (group II) using parasite macroscopic and microscopic research at autopsy. The 10 cats from group III were untreated (control group). The authors observed 100% drug efficacy, at all observation periods, by total interruption of parasite's biological cycle in each of the treated animals. All the control group developed Lagochilascaris minor infection.

【 授权许可】

Unknown