A folow-up period of 13 years prospective study in 190 chagasic patients of Mambaí, Goiás, State, Brazil

Revista da Sociedade Brasileira de Medicina Tropical

Universidade de Brasília, Brasília, Brasil¹  Faculdade de Medicina do Triângulo Mineiro, Uberaba¹  Prata, Aluizio¹  Macêdo, Vanize¹  Castro, Cleudson¹ 

关键词: Evolution of chagasic cardiopathy;    Progression of megaesophagus;    Prospective study;   

DOI  :  10.1590/S0037-86822001000400001

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

A prospective study was performed on the clinical, electrocardiographic (ECG) and radiologic aspects of the esophagus in 190 chagasic patients, for on average follow-up period of 13 years. We found 108 (56.8%) patients who remained in the same clinical state, 72 (37.9%) patients with progressive illness and 10 (5.3%) patients whose previous ECG abnormalities subsided. Thirty nine out of 72 patients with progressive disease developed cardiopathy or aggravation of previous illness, 32 developed into megaesophagus or an existing picture deteriorated and 12 developed or showed worsening of the colopathy. Of 72 patients, 11 presented with associated forms. The development of cardiopathy was greater in males 29.6% (21/71) than in females 15.1% (18/119), p =0.015. There were 19 new cases of cardiopathy, and 20 of aggravated previous disease. The incidence of megaesophagus was 14.9% (23/154), with nine patients whose previous disease worsened. The progression of colopathy was greater in females 9.2% (11/119) than in males 1.4% (1/71), p = 0.026.

【 授权许可】

Unknown