Electrophysiological manifestations in adults with HIV/AIDS submitted and not submitted to antiretroviral therapy

Pró-Fono Revista de Atualização Científica

Matas, Carla Gentile¹  Silva, Sara Manami¹  Gonçalves, Isabela Crivellaro¹  Marcon, Bruna de Almeida¹  Universidade de São Paulo¹ 

关键词: HIV;    Antiretroviral Therapy;    Highly Active;    Hearing;    Evoked Potentials;    Auditory.;   

DOI  :  10.1590/S0104-56872010000200007

学科分类：医学（综合）

来源: Pró-Fono Produtos Especializados para Fonoaudiologia Ltda.

【 摘 要 】

BACKGROUND: auditory evoked potentials (AEP) assess the neuroelectric activity on the auditory pathway -from the auditory nerve to the cerebral cortex - in response to an acoustic stimulus or event. Studies have demonstrated electrophysiological abnormalities in individuals with HIV/AIDS.AIM: to characterize the hearing electrophysiological manifestations in adults with HIV/AIDS by comparing the results obtained in the group exposed to antiretroviral therapy with those obtained in the group not exposed to such treatment. METHOD: electrophysiological evaluation of hearing (Auditory Brainstem Response - ABR, Auditory Middle Latency Reponse - AMLR and P300) was conducted in 56 individuals with HIV/AIDS: 24 participants composed group I (not exposed to antiretroviral treatment) and 32 participants composed group II (exposed to treatment).RESULTS: alterations in every AEP were observed in individuals with HIV/ AIDS, especially in the ABR. Indeed, the group exposed to antiretroviral treatment presented more alterations. CONCLUSION: individuals with HIV/AIDS may present alterations on the central and peripheral auditory nervous system. The group exposed to antiretroviral therapy presents more alterations on the brainstem auditory pathway.

【 授权许可】

Unknown