Caesarean section wound infiltration with ropivacaine versus placebo: Survey of chronic pelvic pain after 4 years' follow-up

South African Journal of Obstetrics and Gynaecology

Justus Hofmeyr¹  Morire Labeodan³  Anthony Akinloye Bamigboye² 

[1] Effective Care Research Unit, University of the Witwatersrand, Johannesburg, South Africa; Fort Hare/Eastern Cape Department of Health, South Africa;Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of there Witwatersrand, Johannesburg, South Africa; Effective Care Research Unit, University of the Witwatersrand, Johannesburg, South Africa;Easydat Consulting and Projects, Nelspruit, Mpumalanga, South Africa

关键词: Key words: pain;    postcaesarean;    pelvic;    local anaesthetic;   

DOI  :  

学科分类：农业科学（综合）

来源: South African Medical Association

【 摘 要 】

Objective. To test the hypothesis that optimal management of postoperative pain may reduce the risk of developing chronic pelvic pain in women who undergo caesarean section.Methods. In a randomised trial in 2006/2007, ropivacaine was infiltrated through all the layers of the anterior abdominal wound in patients undergoing caesarean section. The outcome was a reduction in severe pain or the need for rescue narcotic analgesia within 1 hour after the operation in the ropivacaine group compared with a placebo group (relative risk 0.51; 95% confidence interval 0.38 - 0.69). A follow-up study 4 years later was designed to assess the prevalence of chronic pelvic pain by carrying out telephonic interviews with these women, of whom 77 were contactable and 75 were analysed. Data and statistical analysis were done using Microsoft Excel (2007), Epi Info (version 343) statistical and Review Manager 5 software. Results. Three out of 40 women in the ropivacaine group and 3/35 in the placebo group had persistent pelvic pain (total rate of chronic pelvic pain 8.1%).Conclusion. There was no significant difference in the prevalence of chronic pelvic pain between the ropivacaine wound infiltration group (7.5%) and the placebo group (8.6%) after 4 years’ follow-up. 

【 授权许可】

Unknown