Early renal surveillance: A necessity in a child with tuberous sclerosis complex

South African Journal of Child Health

Santosh Prabhu²  Sijo K John¹  Vijay Kumar²  Sundeep P Thotan²  P L N G Rao⁴  Bikram Kharga²  Ravikiran Nalla³ 

[1] Department of Paediatric Surgery, Kasturba Medical College, Manipal University, Manipal, India;Department of Surgery, Kasturba Medical College, Manipal University, Manipal, India;Vice-Chancellor, Manipal International University, Nilai, Malaysia

关键词: Tuberous sclerosis;    renal cell carcinoma;    angiomyolipoma;    shagreen patches;    ash-leaf-shaped macules;    angiofibromas;   

DOI  :  

学科分类：农业科学（综合）

来源: Health and Medical Publishing Group

【 摘 要 】

Tuberous sclerosis complex (TSC) is an extremely variable genetic disorder that can affect virtually any organ in the body. Disease manifestations continue to develop over the lifetime of an affected individual. Many manifestations can be life threatening; appropriate surveillance and management are necessary to limit morbidity and mortality in this disease. We report a case of an 8-year-old girl with TSC and bilateral renal cell carcinoma, which is usually thought to be a complication diagnosed in adulthood. Our report emphasises the need for frequent surveillance and renal imaging in paediatric patients with TSC. 

【 授权许可】

Unknown