Extraction and Evaluation of Antibacterial Activity from Selected Flowering Plants | Science Publications

American Medical Journal

Erlina Abdullah¹  Parveen Jamal¹  Raha A. Raus¹ 

关键词: Extraction process;    antibacterial activity;    B. subtilis growth;    Spathiphyllum cannifolium;    zone of inhibition;    synthetic antibiotics;    phytochemical groups;    Mueller Hinton Broth (MHB);    Staphylococcus aureus;    test microorganisms;    flowering plants;   

DOI  :  10.3844/amjsp.2012.27.32

学科分类：基础医学

来源: Science Publications

【 摘 要 】

The huge diversity of Malaysian flora has various chemical constituents that make them as outstanding natural product candidates for the treatment of infectious diseases. The screening practice for phytochemical compound in them is essential to explore more natural sources to replace synthetic antibiotics, which generally have side effects such as hypersensitivity, immune-suppression and allergic reactions. Antibacterial activities have been detected in some of the Malaysian plants and most of the Malaysian medicinal plants have been screened for this property. However, so far no study has focus on Malaysian flowering plants yet. In this study, the extraction and determination of antibacterial property from 19 Malaysian flowering plants were conducted. The plants were extracted with methanol, ethyl acetate, hexane and distilled water, individually at concentration of 0.1g mL^-1. The extraction process condition was set to 300 rpm agitation for 10 h at room temperature. The crude extracts of each plant (5 mg/disc) were tested against Bacillus subtilis and Escherichia coli using agar disc diffusion assay method. The screening results showed that ethyl acetate extract of Spathiphyllum cannifolium (

【 授权许可】

Unknown