Effects of Low-Intensity Continuous Ultrasound on Hematological Parameters of Rats

Journal of Biomedical Physics and Engineering

P Basir¹  H Ghaheri¹  M Mehrpour¹  B Jamei¹  M B Shiran¹  A Shakeri-Zadeh¹ 

关键词: Low Intensity Ultrasound;    Continuous Wave;    Blood Cells;    Hematological Test;    Biological Effects;   

DOI  :  

学科分类：生物科学（综合）

来源: Shiraz University of Medical Sciences

【 摘 要 】

Background:Low intensity ultrasound (US) has some well-known bio-effects which are of great importance to be considered. Objectives:We conducted the present study to investigate the effects of low intensity continuous ultrasound on blood cells count in rat. Methods:Rats were anesthetized and blood samples were collected before US exposure. Then, they were exposed to US with nominal intensity of 0.2 W/cm 2at frequency of 3 MHz for a period of 10 minutes and this protocol was repeated for 7 days. Twenty four hours after the last US exposure, secondary blood samples were collected and the changes in blood parameters were evaluated.Results:Analysis revealed that platelets, hematocrit (HCT) and hemoglobin (HGB) were significantly different between experimental and sham groups but no difference between sham and control groups was observed. The results show that HCT and HGB of exposed rats were significantly reduced.Conclusion:This study shows that low intensity US may lead to side effects for hematological parameters such as reduction in the levels of HGB and HCT. 

【 授权许可】

Unknown