A mixture of chamomile and star anise has anti-motility and antidiarrheal activities in mice

Revista Brasileira de Farmacognosia

Benemérita Universidad Autónoma de Puebla, Puebla, México¹  Treviño, Samuel¹  Vargas-Perez, Izel¹  Aguilar-Cruz, Lidia¹  Díaz, Alfonso¹  Calva-Rodríguez, Roberto¹  Contreras-Mora, Irma Rosalía¹  Venegas, Berenice¹ 

关键词: Chamomile;    Star anise;    Intestinal motility;    Castor oil;    Antidiarrheal;   

DOI  :  10.1016/j.bjp.2014.07.016

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

Diarrhea is a serious public health problem in Mexico and other countries. A widely used alternative in the treatment of diarrhea is the use of herbal medicines. Infusions of chamomile and star anise possess anti-inflammatory and antimotility properties that could help alleviate gastrointestinal disorders. The aim of this study was to determine the effect of the mixture of chamomile and star anise infusions on gastrointestinal activity in mice. A gastrointestinal assessment of the mixture of chamomile and star anise was carried out in mice, and the percentage of advance of administered activated carbon through the intestinal tract of the animals was measured. Furthermore, the diarrhea model was induced with castor oil. The infusions were prepared using a mix with a 50:50 ratio of the herbs, and were administered at Mix-10, 20, 40 and 80 (mg/kg) orally. The results indicate that Mix-40 and Mix-80 decreased the completion percentage of the activated carbon, delayed the appearance of diarrhea and decreased the number of evacuations in comparison with the control group. This suggests that the combination of chamomile and star anise can be used as an alternative antidiarrheal treatment.

【 授权许可】

Unknown