Ethnobotanical, pharmacognostical, pharmacological and phytochemical studies on Smilax domingensis in Guatemala

Revista Brasileira de Farmacognosia

Gaitán, Isabel¹  Universidad Nacional de Rosario, Argentina¹  Cáceres, Armando¹  Gattuso, Martha¹  Martínez, Vicente¹  Santizo, Aylin¹  Gattuso, Susana¹  Cruz, Sully M.¹  Universidad de San Carlos, Guatemala¹ 

关键词: antimicrobial;    characteristics;    immunomodulator;    micrographic;    zarzaparrilla;   

DOI  :  10.1590/S0102-695X2011005000211

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

Smilax domingensis Willd., Smilacaceae, known as zarzaparrilla, is a climbing shrub from Tropical America. The rhizome is popularly used in medicine as anti-inflammatory, antiseptic, and tonic. Since 1983 studies are being conducted in Guatemala for validation of the ethnobotanical uses, particularly in vitro demonstration of antimicrobial activity, using wild material, with high variability and some taxonomic problems. This article reports the taxonomic determination, cultivation of drug material, evaluation of use by in vitro and in vivo pharmacological assays, and phytochemical characterization. Extracts from cultivated material was evaluated by antimicrobial, anti-inflammatory, analgesic and immunomodulatory models, confirming the antimicrobial and immunomodulatory activities. Phytochemistry was done in the crude drug and extracts. Quality control parameters are described (micrographic drawings and phytochemical characteristics). Evidence is presented that cultivated rhizome has antimicrobial and immunomodulatory activities, validating the popular use and helping the industrial development of phytopharmaceutical products.

【 授权许可】

Unknown