Antioxidant activities of Juniperus foetidissima essential oils against several oxidative systems

Revista Brasileira de Farmacognosia

Airin, A.¹  Aslani, S.¹  Emami, S. A.¹  Kasher, T.¹  Sahebkar, A.¹  Tehran University of Medical Sciences, Iran¹  Mashhad University of Medical Sciences, Iran¹  Isfahan University of Medical Sciences, Iran¹  Naderi, G. A.¹  Asgary, S.¹  Ardekani, M. R. Shams¹ 

关键词: anti-glycation;    antioxidant;    Cupressaceae;    essential oil;    Juniperus foetidissima;   

DOI  :  10.1590/S0102-695X2011005000120

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

The present study aimed to evaluate the antioxidant activity of essential oils obtained from branchlets of male and female trees as well as fruits of Juniperus foetidissima Willd., Cupressaceae, from Iran. For this purpose, essential oils of J. foetidissima were phytochemically analyzed and different concentrations of them were tested in five oxidative systems: 1) low-density lipoprotein oxidation; 2) linoleic acid peroxidation; 3) red blood cell hemolysis; 4) hemoglobin glycation; and 5) insulin glycation assays. In all employed systems, antioxidant effects were observed from the three tested oils though in varying degrees. The most promising activities of the oils were observed against hemoglobin and insulin glycation. Antioxidant activities of the oils did not appear to be dose-dependent. In addition, no consistent superiority in antioxidant effects was observed from a single oil in different assays. In view of the current results, J. foetidissima branchlet and fruit oils could be regarded as effective natural products with anti-glycation activity.

【 授权许可】

Unknown