Revista Brasileira de Farmacognosia | |
Genotoxicity and cytotoxicity of Erythrina velutina Willd., Fabaceae, on the root meristem cells of Allium cepa | |
Empresa Brasileira de Pesquisa Agropecuária, Aracaju, Brazil1  Estevam, Charles S.1  Pantaleao, Silmara M.1  Universidade Federal do Rio Grande do Norte, Natal, Brasil1  Oliveira, Betejane de1  Silva, Déborah S. B. S.1  Universidade Federal de Sergipe, São Cristóvão, Brasil1  Scher, Ricardo1  Mata, Samuel S.1  Garcia, Anuska C. F. S.1  Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brasil1  | |
关键词: Erythrina velutina; Allium cepa; root growth; mitotic index; chromosomal aberration; | |
DOI : 10.1590/S0102-695X2011005000024 | |
来源: Sociedade Brasileira de Farmacognosia | |
【 摘 要 】
The effects of the decoction of Erythrina velutina Willd., Fabaceae, were investigated using the root meristem cells of Allium cepa L., Amaryllidaceae. Ten concentrations of the aqueous extract (0.125 to 1.25%) of this medicinal plant were analyzed at both macroscopic and microscopic levels. All concentrations showed root growth inhibition after 96 h treatment. Although there were no significant differences between the mitotic indexes of any concentration and the control, there were changes in the frequencies of cell stages at three different concentrations. Additionally, the presence of five different cells abnormalities was recorded: chromosome bridging, lagging chromosomes, chromosome fragments, disturbed metaphase and disturbed anaphase. These results suggest inhibitory and genotoxic activity of the decoction of E. velutina on Allium cepa.
【 授权许可】
Unknown
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